EA's Godfather II is expanding upon the GTA-esque open world, mission-based gameplay by adding a Real Time Strategy (RTS) element to it.
To help players manage their empire, The Godfather II introduces “The Don’s View” – an innovative strategy meta-game that allows players to oversee the entire world as they grow the family business. Using the Don’s View, players will be able to build, defend and expand their crime rings, while keeping an eye on the movements and plans of the rival families.
This sounds like a great addition, although I'm skeptical if it's one of those, "just because you can doesn't mean you should," sort of things.
The original Godfather game was quite fun, so hopefully this one will be as well. The game is due out in February of '09, but there is a, "premiere exclusively on GameTrailers TV with Geoff Keighley on Friday, August 15th on Spike TV."